Rapid onset pressor and sympathetic responses to static handgrip in older hypertensive adults
نویسندگان
چکیده
منابع مشابه
Exaggerated sympathetic and pressor responses to handgrip exercise in older hypertensive humans: role of the muscle metaboreflex.
Recent animal studies have reported that exercise pressor reflex (EPR)-mediated increases in blood pressure are exaggerated in hypertensive (HTN) rodents. Whether these findings can be extended to human hypertension remains unclear. Mean arterial pressure (MAP), muscle sympathetic nerve activity (MSNA), and venous metabolites were measured in normotensive (NTN; n = 23; 60 ± 1 yr) and HTN (n = 1...
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IN 1895 Leonard Hill' concluded from his experimental work on the blood pressure and heart rate of animals that the effect of changing the position afforded a most delicate test of the vasomotor mechanism. The development of accurate methods of continuous recording made it possible to confirm these conclusions in man. Previous studies2 3 of normal subjects established a definite pattern of bloo...
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Cardiac and peripheral vasomotor factors contribute to the rapid pressor response at the onset of isometric handgrip exercise. We tested the hypothesis that age enhances the sympathetic and vasoconstrictor response at the onset of isometric handgrip exercise so that the pressor response is maintained, despite a diminished cardiac function. Twelve young and twelve older (24 ± 3 and 63 ± 8 yr) in...
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Intraventricular administration of nicotine produced a biphasic effect, consisting of an initial rise than a slight fall in blood pressure in unanaesthetized rats. Spontaneously hypertensive rate (SHR) showed increased pressor responses, but these responses were within normal limits in renal hypertensive and DOCA-saline hypertensive rats. The blood pressure response to nicotine in SHR was aboli...
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IN previous studies, pressor reactivity to several standardized noxious stimuli was evaluated quantitatively, and increased responsiveness was demonstrated in hypertensive as compared with normotensive subjects." 2 The stimuli employed in these studies included simple psychologic provocation as well as the cold pressor test and the intravenous injection of a small dose of angiotensin II. Differ...
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ژورنال
عنوان ژورنال: Journal of Human Hypertension
سال: 2014
ISSN: 0950-9240,1476-5527
DOI: 10.1038/jhh.2014.106